Antimicrobial Activity of copyright Surfactants with Azapolymethylene Spacer

Antimicrobial Activity of copyright Surfactants with Azapolymethylene Spacer

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A series of 21 azapolymethylene copyright surfactants were obtained.The synthesis of the title surfactants in one- or two-step reaction proceeds with good yields.The structure ngetikin and the purity of the synthesized compounds were determined by 1H and 13C NMR, ESI-MS spectra, and elemental analysis.Moreover, 2D COSY, HMBC, and HSQC spectra were performed.The minimal inhibitory concentrations (MIC) of the synthesized compounds were determined against fungi: Candida albicans, Aspergillus niger, Penicillium chrysogenum and bacteria: Escherichia coli,Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis.

Also, the critical micelle concentrations (CMC) were determined.The relationship deus gorras between antimicrobial and surface activity and surfactant structure has been determined.